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Vardenafil increases coronary flow response to hypercapnic acidosis in isolated guinea pig heart
Markus Brand1, Andreas Deussen
1Department of Physiology, Medical Faculty Carl Gustav Carus TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Basic Research in Cardiology
|October 26, 2006
Abstract:
The hypothesis was tested that vardenafil, a PDE5 inhibitor, specifically enhances coronary vasodilation during acidosis. In isolated constant pressure perfused guinea pig hearts, infusion of vardenafil (
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