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Published on: October 21, 2022
[The different opacity patterns of Lisch corneal dystrophy].
S Butros1, G K Lang, J Alvarez de Toledo
1Universitäts-Augenklinik Ulm, Ulm. susanne@butros.de
Summary
Lisch corneal dystrophy presents with unique microcyst patterns visible under slit-lamp examination. Exact analysis of these opacity patterns aids in differentiating Lisch corneal dystrophy from other epithelial corneal dystrophies.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Genetic Eye Disorders
Background:
- Lisch corneal dystrophy is an epithelial corneal dystrophy characterized by diffuse gray opacities.
- These opacities manifest in various patterns under direct illumination and consist of microcysts upon retroillumination examination.
Observation:
- Three patients with Lisch corneal dystrophy were examined using slit-lamp biomicroscopy.
- Corneal opacities were documented photographically under direct and retroillumination.
Findings:
- All patients exhibited characteristic intraepithelial, densely crowded clear microcysts in retroillumination.
- Observed opacity patterns included radial, club-shaped, and feathery gray opacities in the corneas.
Implications:
- Exact analysis of opacity patterns and units via slit-lamp examination can differentiate Lisch corneal dystrophy from other epithelial corneal dystrophies.
- This diagnostic approach aids in accurate classification and management of corneal dystrophies.

