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Published on: March 14, 2025
[Analysis of apposition on differently treated implant surface at early stage of implantation]
Fu-ming He1, Song Chen, Shan-shan Zhao
1The Affiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Objective:
To compare the surface apposition and the bone response at early period of implantation in two differently treated implants.
Methods:
The implants were subject to double acid-etched-H2O2/HCl-heat treatment and double acid-etching treatment, and then randomly implanted into the tibia of rabbits. After 2, 4, 8 weeks of follow up, the bone specimens containing implants were prepared and examined by a field emission SEM and EDX.
Result:
A layer rich with calcium and phosphorus was clearly demonstrated on the implants surface of both groups after 2 weeks of implantation, but it was mostly disappeared after 4 weeks. There were large amounts of osteoblasts cells on double acid-etched-H2O2/HCl-heat treated implants surface indicating the initiation of osteogenesis. After 8 weeks of implantation some new bones were attached on the implants surface in both groups, more bones attached were shown on double acid-etched- H2O2/HCl-heat treated implants surface.
Conclusion:
A calcium and phosphorus-rich layer was formed on the implants surface of both groups at early period of implantation.

