Related Experiment Video
Updated: Jul 19, 2026

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood
Published on: February 11, 2017
Emotion regulation in children and adolescents: boundaries between normalcy and bipolar disorder
Daniel P Dickstein1, Ellen Leibenluft
1Mood and Anxiety Disorder Program, National Institute of Mental Health, Bethesda, MD 20892-2670, USA. dicksted@mail.nih.gov
Abstract:
Much controversy has surrounded the diagnosis of bipolar disorder (BD) in children and adolescents. However, recent work from an affective neuroscience perspective has advanced what is known about the boundaries of emotion regulation in BD compared to typically developing youth. In this article, we first briefly review the clinical issues that have contributed to this diagnostic controversy. Second, we discuss our phenotyping system, which can be used to guide neurobiological research designed to address these controversial issues. Third, we review what is known about the fundamentals of emotion regulation in human and nonhuman primate models. Fourth, we present recent data demonstrating how children and adolescents with BD differ from those without psychopathology on measures of emotion regulation. Taken as a whole, this work implicates a neural circuit encompassing the prefrontal cortex, amygdala, and striatum in the pathophysiology of pediatric BD.
Related Concept Videos
Bipolar Disorder
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Oppositional Defiant Disorder
Diagnostic Criteria and...
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Mania and Antimanic Drugs: Overview
Self-Discrepancy Theory
