Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Imaging study scores for ankylosing spondylitis.

Daniel Wendling1, Eric Toussirot, Gérald Streit

  • 1Rheumatology Department, Jean-Minjoz Teaching Hospital, Boulevard Fleming, 25030 Besançon cedex, France. daniel.wendling@ufc-chu.univ-fcomte.fr

Joint Bone Spine
|October 27, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spondyloarthritis and inflammatory bowel disease: towards a more severe and refractory disease phenotype.

EULAR rheumatology open·2026
Same author

Discrepancies in the assessment of axial spondyloarthritis between patients and rheumatologists: what does this mean?

Clinical rheumatology·2026
Same author

Late-onset psoriatic arthritis: A separate entity.

Joint bone spine·2026
Same author

Bacterial translocation and intestinal permeability in early axial spondyloarthritis association with 5-year outcomes: insights from the DESIR cohort.

Rheumatology (Oxford, England)·2026
Same author

Clinical Images: A painful bipartite patella.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

Dubious benefit of three injections of botulinum toxin in refractory chronic neck pain: Retrospective data on 22 patients with a 9-month follow-up.

Joint bone spine·2026

Ankylosing spondylitis (AS) assessment uses radiographic and MRI scores. While MRI shows inflammation changes with TNF antagonists, radiographic scores like mSASSS reflect slower structural alterations, indirectly supporting treatment effects.

Area of Science:

  • Rheumatology
  • Medical Imaging
  • Clinical Trials

Background:

  • Scoring systems for ankylosing spondylitis (AS) exist for both radiography and MRI.
  • Radiographic scores capture slow-progressing chronic changes, limiting short-term sensitivity.
  • Magnetic resonance imaging (MRI) effectively detects inflammation, particularly in the spine.

Purpose of the Study:

  • To review current scoring systems for ankylosing spondylitis (AS).
  • To compare the sensitivity to change of radiographic versus MRI scoring methods.
  • To discuss the role of these scores in evaluating treatment effects, such as with TNF antagonists.

Main Methods:

  • Review of existing scoring systems for AS, including mSASSS (modified Stoke Ankylosing Spondylitis Spine Score).

Related Experiment Videos

  • Analysis of studies utilizing radiographic and MRI assessments in AS patients.
  • Discussion of MRI's sensitivity to change in patients treated with TNF antagonists.

    • Main Results:

    • The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) evaluates cervical and lumbar spine structural changes.
    • TNF antagonists have demonstrated an ability to modify the mSASSS, suggesting a structural impact.
    • MRI is highly sensitive to inflammatory changes in the spine, especially in patients receiving TNF antagonists.

    Conclusions:

    • MRI is a sensitive tool for monitoring spinal inflammation in ankylosing spondylitis (AS) patients, particularly during TNF antagonist therapy.
    • Radiographic scores like mSASSS reflect slower structural changes but indirectly support the efficacy of treatments like TNF antagonists.
    • Standardization of MRI scoring for spine and sacroiliac joints is an ongoing effort by the OMERACT task force.