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Updated: Jul 19, 2026

Determining the Serum Stability of Human Adenosine Deaminase 1 Enzyme
Published on: September 27, 2024
Adenosine kinase from rat liver: new biochemical properties
R Leoncini1, D Vannoni, A Santoro
1Department of Internal Medicine, Endocrine-Metabolic Sciences and Biochemistry University of Siena, Siena, Italy.
Abstract:
Adenosine kinase is a well-known enzyme which catalyzes the phosphorylation of adenosine to AMP: Its metabolic and kinetic properties are well studied. Here, we report new properties of rat liver enzyme, demonstrating a new reaction: ADP can be a phosphate donor instead ATP, according to the reaction: adenosine + ADP --> 2AMP) demonstrating the efficiency of AdK to phosphorylate adenosine, also starting from ADP. Cells could exploited this property in situations in which ATP levels are strongly decreased and ADP decreases slowly.
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