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Effect of endocervical-specimen adequacy on detection of Chlamydia trachomatis by the APTIMA COMBO 2 assay
C K Rogers1, B J Wood, P Rizzo
1Wyoming Public Health Laboratory, 517 Hathaway Bldg., 2300 Capitol Ave., Cheyenne, WY 82002, USA. croger@state.wy.us
Journal of Clinical Microbiology
|October 27, 2006
Abstract:
Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P=0.27), the study suggested no difference in positivity rates due to specimen adequacy when this amplified technology was used.