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Updated: Jul 19, 2026

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
Sex-sorted sperm and fertility: an alternative view
Valerie J Grant1, Lawrence W Chamley
1Department of Psychological Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand. vj.grant@auckland.ac.nz
Abstract:
Although contemporary methods of physically separating X from Y chromosome-bearing spermatozoa are now very efficient, overall fertility rates following the use of sex-sorted sperm are not as impressive, in spite of many attempts to improve them. At the same time, there are suggestions from evolutionary biology, and from sex allocation theory in particular, that there may need to be a modification to the chance theory of sex determination in mammals. This is because it now appears that the mammalian female could have some influence on the sex of her offspring, and furthermore, that this influence could be preconceptual. If so, this could go some way towards accounting for the putative inefficiencies in fertilization following insemination with sex-sorted sperm.
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