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Continuation of proton pump inhibitors from hospital to community
Kenneth Grant1, Noor Al-Adhami, June Tordoff
1Pharmacy Department, Dunedin Hospital, Dunedin, New Zealand.
Insights
Many patients inappropriately start proton pump inhibitor (PPI) treatment, with poor discharge information leading to continued use. Improved clinical indication and communication are needed for effective PPI management.
Area of Science:
- Gastroenterology
- Internal Medicine
- Pharmacology
Background:
- Proton pump inhibitors (PPIs) are widely used medications.
- Assessing the appropriate initiation and continuation of PPI therapy is crucial for patient care.
- Hospital discharge practices can significantly impact long-term medication management.
Purpose of the Study:
- To evaluate the appropriateness of initiating proton pump inhibitor (PPI) treatment during hospitalization.
- To assess the quality of discharge information provided to patients and general practitioners (GPs).
- To determine the association between hospital initiation and continued PPI treatment in the community.
Main Methods:
- A survey was conducted on inpatients newly initiated on a PPI between June and August 2003.
- The appropriateness of PPI therapy initiation was assessed.
- Discharge information completeness and PPI continuation at 6 months post-discharge were evaluated.
Main Results:
- 60% of patients were appropriately initiated on PPI treatment.
- Less than 25% of discharge summaries included recommendations for PPI treatment duration or review.
- Appropriateness of initiation did not significantly influence long-term treatment duration, with many patients continuing PPIs regardless of initial indication.
Conclusions:
- Proton pump inhibitors (PPIs) should be initiated only when clinically indicated.
- Discharge information, particularly regarding PPI treatment duration and dose titration, needs enhancement for better continuity of care.
- Improved communication between hospital and community care providers is essential for optimizing PPI use.
Objectives:
To evaluate the appropriateness of initiation of proton pump inhibitor (PPI) treatment in hospital, the quality of discharge information, and any association with continued treatment in the community.
Method:
Survey of all inpatients newly initiated on a PPI in June-August 2003. Assessment of appropriateness of therapy and completeness of discharge information; assessment of continuation of PPI therapy in the community after 6 months.
Results:
Thirty-five of 58 patients (60%) were considered appropriately commenced on PPI treatment. Less than 25% of patients discharged on a PPI had discharge information recommending duration of treatment or review. In the "appropriate" group 30 patients (86%) were discharged on omeprazole, and 13/21 (62%) evaluable patients remained on this at 6 months. In the "inappropriate" group 15 (65%) were discharged on omeprazole, and 10/14 (71%) evaluable patients remained on this at 6 months. Older patients remained on omeprazole for a longer duration but appropriateness of commencement did not influence the duration of treatment. Dose titration was attempted for 10 (29%) patients including three from the "inappropriate" group.
Conclusion:
Care should be taken to commence PPIs only when clinically indicated. Discharge information to GPs, especially recommendations for duration of treatment and/or dose titration, requires improvement.
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