Related Experiment Video
Updated: Jul 19, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Blood transfusionist extraordinaire: Marie Cutbush Crookston
1k.burnie@sympatico.ca
After receiving her BSc from the University of Melbourne, Australia, Marie set sail for England to pursue a career. In London, she worked with Dr P.L. Mollison for 10 years, and together they published many articles in the areas of hemolytic disease of the newborn, red cell survival, red cell preservation, and the identification of new antibodies. In 1957, she married Dr John Crookston and moved to Toronto. In Toronto, she directed and participated in various research projects while acting as a consultant to the Blood Transfusion Laboratory at Toronto General Hospital. Her enthusiasm for the field of Transfusion Medicine, her keen eye, and intellect resulted in many discoveries, both on her own or in collaboration with others. Marie is now retired but is fondly remembered by Blood Transfusionists in Canada and elsewhere.
After receiving her BSc from the University of Melbourne, Australia, Marie set sail for England to pursue a career. In London, she worked with Dr P.L. Mollison for 10 years, and together they published many articles in the areas of hemolytic disease of the newborn, red cell survival, red cell preservation, and the identification of new antibodies. In 1957, she married Dr John Crookston and moved to Toronto. In Toronto, she directed and participated in various research projects while acting as a consultant to the Blood Transfusion Laboratory at Toronto General Hospital. Her enthusiasm for the field of Transfusion Medicine, her keen eye, and intellect resulted in many discoveries, both on her own or in collaboration with others. Marie is now retired but is fondly remembered by Blood Transfusionists in Canada and elsewhere.
Related Concept Videos
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Blood Types
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Fluid Connective Tissues: Blood and Lymph
Blood
The blood flows through blood vessels— arteries, capillaries, and veins. Blood plasma is primarily made of proteins, solutes, and water.

