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Related Concept Videos

Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

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Related Experiment Video

Updated: Jul 19, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

[Pulmonary embolism and Behçet's disease].

S Hammami1, F Addad, N Kaoubaa

  • 1Service de médecine interne, faculté de médecine Monastir, Tunisie. sonia.hammami@fmm.rnu.tn

Archives Des Maladies Du Coeur Et Des Vaisseaux
|October 28, 2006
PubMed
Summary

Pulmonary embolism is a rare but serious complication of Behçet's disease. Hyperhomocysteinemia may contribute to its development, suggesting folate therapy could be beneficial.

Related Experiment Videos

Last Updated: Jul 19, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Area of Science:

  • Vascular Medicine
  • Rheumatology
  • Hematology

Context:

  • Behçet's disease is a rare multisystemic inflammatory disorder.
  • Pulmonary embolism (PE) is an uncommon but severe complication of Behçet's disease.
  • Understanding the characteristics of PE in Behçet's disease is crucial for patient management.

Purpose:

  • To analyze the epidemiological, physiopathological, and evolutive aspects of pulmonary embolism in Behçet's disease patients.
  • To identify potential contributing factors and treatment outcomes for PE in this specific patient cohort.

Summary:

  • A study of seven Behçet's disease patients with pulmonary embolism revealed common presentations including thrombosis and aneurysm.
  • Normal levels of Protein C, Protein S, and antithrombin III were observed, but hyperhomocysteinemia was present in five patients.
  • Successful treatment involved anticoagulation, high-dose prednisone, colchicine, and cyclophosphamide, with a suggestion that hyperhomocysteinemia may play a pathogenic role.

Impact:

  • Pulmonary embolism represents a severe manifestation of Behçet's disease with a poor prognosis.
  • Hyperhomocysteinemia may be a significant factor in the pathogenesis of PE in Behçet's disease.
  • Early immunomodulation therapy combined with folate may help manage hyperhomocysteinemia and improve outcomes.