Related Experiment Video
Updated: Jul 19, 2026
Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
[Percutaneous closure of three septal defects by two Amplatz occluders implanted during the same procedure]
Insights
Interventional catheterization successfully closed multiple atrial septal defects in a 63-year-old woman. Two Amplatz devices were implanted, resolving cardiac failure symptoms and showing no residual shunt post-procedure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Accurate morphological evaluation is crucial for interventional closure of multiple atrial septal defects.
- Key assessment parameters include defect number, proximity to cardiac structures, and septal resistance.
Observation:
- A 63-year-old woman presented with cardiac failure.
- Diagnosis revealed three distinct atrial septal defects.
Findings:
- All three atrial septal defects were successfully closed using interventional catheterization.
- Two Amplatz devices were implanted to achieve defect closure.
- Post-procedure echocardiography at six months confirmed normal device position and no residual shunt.
Implications:
- Interventional catheterization is a viable treatment for multiple atrial septal defects.
- Successful closure leads to symptom resolution and improved cardiac function.
- This approach offers a minimally invasive alternative for complex septal defect management.
Abstract:
Multiple atrial septal defects can be closed by interventional catheterisation. The procedure requires an accurate morphological evaluation: number of defects, distance from their edges to the main cardiac structures, resistance of the septum. The authors report the case of a 63 year old woman presenting with cardiac failure in whom 3 atrial septal defects were diagnosed. All 3 defects were successfully closed by the implantation of two Amplatz devices. Control echocardiography at 6 months showed the occluders in a normal position with no residual shunt and the patient was asymptomatic.
