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Updated: Jul 19, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Head trauma
V Bonhomme1, P Hans, J Fr Brichant
1Service Universitaire d'Anésthesie-Réanimation, CHR de la Citadelle, CHU de Liége, Belgium. vincent.bonhomme@chu.ulg.ac.be
Insights
This review outlines essential principles for managing head trauma, covering initial assessment, monitoring, and specialized care for pediatric patients. It details critical aspects from acute resuscitation to long-term management strategies.
Area of Science:
- Neuroscience
- Trauma Surgery
- Critical Care Medicine
Background:
- Head trauma is a significant cause of morbidity and mortality.
- Effective management requires a multidisciplinary approach and adherence to established protocols.
Purpose of the Study:
- To present widely accepted principles for the comprehensive management of head trauma patients.
- To cover both acute and secondary phases of patient care.
Main Methods:
- Review of current literature and clinical guidelines.
- Synthesis of established protocols for head trauma management.
Main Results:
- Detailed description of initial evaluation, resuscitation, and radiological assessment.
- Emphasis on intracranial pressure and cerebral perfusion pressure management.
- Discussion of brain protection, organ dysfunction, complications, and anesthetic considerations.
- Inclusion of specific guidelines for pediatric head trauma.
Conclusions:
- Adherence to standardized management principles is crucial for optimizing outcomes in head trauma patients.
- Comprehensive care, addressing all phases of management and specific patient populations, is essential.
Abstract:
The aim of this review is to provide the reader with the most commonly accepted principles for the management of head trauma patients. The initial clinical evaluation and resuscitation, radiological evaluation, monitoring, intracranial pressure and cerebral perfusion pressure management, brain protection, associated organ dysfunctions and complications, anaesthetic manage ment and the singularities of paediatric head trauma patients are described, either for the acute phase and the secondary phase of management.
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