Related Experiment Video
Updated: Jul 19, 2026

Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations
Published on: May 31, 2020
Cytotoxic diterpenoids from the soft coral Sarcophyton crassocaule
Cuixian Zhang1, Jun Li, Jingyu Su
1School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
Abstract:
Five new cembrane diterpenoids, sarcrassins A-E (1-5) along with a known compound, emblide (6), have been isolated from the soft coral Sarcophyton crassocaule collected from the Bay of Sanya, Hainan Island, China. The structures of 1-5 were determined by spectroscopic methods including 1D and 2D NMR techniques. Their relative configurations were determined by NMR data and NOESY experiments. Compounds 2, 4, and 6 exhibited significant cytotoxic activities against KB cell lines with IC50 values of 5.0, 4.0, and 5.0 microg/mL, respectively, while compounds 1 and 5 showed moderate cytotoxicity toward KB cell lines with IC50 values of 19.0 and 13.0 microg/mL, respectively.
Related Concept Videos
Diversity of Protists II
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
Drugs that Destabilize Microtubules
Antifungal Agents
Diphtheria
Cytotoxic Edema: Pathophysiology

