[Acral persistent papular mucinosis]

Area of Science:

• Dermatology
• Histopathology

Background:

• Cutaneous mucinoses involve skin mucin deposition, encompassing primary forms like papular mucinosis and systemic associations like scleromyxedema.
• Acral persistent papular mucinosis (APPM) is a distinct subtype, localized to the hands and forearms without systemic involvement.

Observation:

• A 52-year-old healthy woman presented with characteristic skin lesions on the dorsal aspects of her hands.
• Histological examination of the lesions was performed to confirm the diagnosis.

Findings:

• The histological study definitively confirmed the diagnosis of Acral persistent papular mucinosis (APPM).
• The patient's presentation and diagnostic findings were consistent with a primary cutaneous mucinosis.

Implications:

• This case reinforces the diagnostic criteria for APPM as a localized cutaneous mucinosis.
• Understanding APPM's distinct presentation aids in differentiating it from other mucinous skin conditions and associated systemic diseases.