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Updated: Jul 19, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Annular elastolytic giant cell granuloma: a case report located in non-sun exposed areas]
Lucía Campos-Muñoz1, Rosa Maria Díaz-Díaz, Alicia Quesada-Cortés
1Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España. luciacampos78@yahoo.es
Abstract:
Annular elastolytic giant cell granuloma (AEGCG) is an uncommon entity clinically characterized by erythematous annular plaques with atrophic and hypopigmented center, that predominates in sun-exposed zones. The histology shows a granulomatous infiltrate without palisading image, made up of lymphocytes, histiocytes and giant cells, with phagocytosis of elastic fibers, without necrobiosis or mucin deposit. We present the case of a male patient with atypical clinical manifestation on the non-sun exposed skin and AEGCG characteristic histology.
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