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Related Experiment Video

Updated: Jul 19, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Associations between psychedelic use, abuse, and dependence and lifetime panic attack history in a representative

Marcel O Bonn-Miller¹, Amit Bernstein, Natalie Sachs-Ericsson

¹The University of Vermont, Burlington, VT, USA.

Journal of Anxiety Disorders

|October 28, 2006

Summary

Psychedelic abuse and dependence, not just use, are linked to a higher risk of panic attacks. This study analyzed data from a Colorado adult population survey to understand this connection.

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Last Updated: Jul 19, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Area of Science:

Psychiatry
Epidemiology
Substance Use Disorders

Background:

Psychedelic substances have been used for various purposes, but their long-term effects on mental health, particularly anxiety disorders, require further investigation.
Understanding the relationship between substance use patterns and panic attacks is crucial for public health.
Previous research has yielded mixed results regarding the impact of psychedelic use on anxiety symptoms.

Purpose of the Study:

To investigate the association between lifetime psychedelic use, abuse, and dependence and the occurrence of panic attacks.
To differentiate the risks associated with mere use versus problematic use (abuse and dependence) of psychedelics.
To contribute to the understanding of the role of psychedelics in the context of panic disorder.

Main Methods:

Utilized data from a statewide epidemiological survey of the Colorado general adult population.
Included a large, representative sample (n=4745) with demographic information (52% female).
Employed statistical analyses to control for theoretically relevant variables when examining the relationship between psychedelic use patterns and panic attacks.

Main Results:

Psychedelic abuse and dependence were significantly associated with an increased lifetime risk of panic attacks.
Simple lifetime psychedelic use, without abuse or dependence, was not significantly related to panic attacks.
Findings were consistent with the study's predictions regarding problematic substance use.

Conclusions:

Psychedelic abuse and dependence represent significant risk factors for experiencing panic attacks.
The distinction between use and abuse/dependence is critical when assessing the mental health risks of psychedelics.
Further research is warranted to elucidate the mechanisms underlying the link between problematic psychedelic use and panic attacks.