Related Experiment Video
Updated: Jul 19, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Unusual, unilateral metastasis of a prostate-carcinoma and palliative rhenium-186 pain-therapy]
I Breidert-Backes1, S Adams, R P Baum
1Klinik für Nuklearmedìzin, Universität Frankfurt am Main, Deutschland.
Abstract:
A 82-year-old male patient had developed a suffering from an unusual unilateral growing bone metastases of a prostate-carcinoma D2 (Histological diagnosis: indifferent, partly cribiform growing prostate-carcinoma, T3N x M1, G3; first diagnosis 7/1988), which suggests a sufferring from M. Paget. In October 1988, the patient underwent a subcapsular orchiectomy, followed by androgene therapy with fugurel. Due to ongoing osseous metastases, in November/December 1992 a radiotherapy of the right hip (50 Gy) was performed. Beginning from October 1994, severe progression of bone metastases was observed with distinct pain-symptoms, leading to an increasing use of analgetics.