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Updated: Jul 19, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
[External therapy with radioactive urine: a pitfall during sceletal scintigraphy]
1Klinik und Poliklinik für Nuklearmedizin, der Universität zu Köln, Deutschland. Klemens.Scheidhauer@medizin.uni-koeln.de
A patient with psoriatic arthritis used radioactive urine to treat skin lesions, leading to unexpected contamination during a bone scan. This highlights potential risks of using unapproved radioactive materials for dermatological conditions.
Area of Science:
- Nuclear Medicine
- Dermatology
- Rheumatology
Background:
- Psoriasis arthropathica (psoriatic arthritis) is a chronic inflammatory condition affecting joints and skin.
- Bone scintigraphy is a nuclear medicine imaging technique used to assess joint inflammation.
Observation:
- A patient with psoriatic arthritis presented for a two-phase bone scan.
- Extensive skin contamination on the extremities was observed in delayed imaging.
Findings:
- The contamination originated from the patient's self-administration of radioactive urine as an embrocation for psoriasis exanthema (skin lesions).
- This resulted in artifactual signals on the bone scan, potentially obscuring or mimicking true joint pathology.
Implications:
- Highlights the critical importance of patient history and awareness of self-administered treatments in interpreting nuclear medicine scans.
- Underscores the potential dangers of using unverified radioactive substances for therapeutic purposes.
- Emphasizes the need for clear patient education regarding the risks associated with experimental or non-standard treatments.
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