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Updated: Jul 19, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
[Stability of busulfan injection solution (Busilvex, Busulfex) in B/Braun Injekt syringes]
1Apotheke des Klinikums der Johannes Gutenberg-Universität Mainz, Germany.
Abstract:
Stability of busulfan injection solution (Busilvex, Busulfex) in B/Braun Injekt syringes Stability of busulfan injection was determined by a modified stability-indicating HPLC method with UV detection. Diethyldithiocarbamate was used as derivatization agent. The stability tests revealed that busulfan injection (Busilvex, Busulfex) stored in B/Braun Injekt syringes at 18-20 degrees C without light protection or refrigerated are stable for up to 28 days. Unused busulfan injection (Busilvex, Busulfex) is not necessarily to be discarded, but can be stored for a prolonged period of time in a rubber free syringe, preferably under refrigeration.
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