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Vascular disrupting agents.

John W Lippert1

  • 1Medicinal Chemistry Department, Albany Molecular Research, Inc., PO Box 15098, Albany, NY 12212-5098, USA. john.lippert@albmolecular.com

Bioorganic & Medicinal Chemistry
|October 31, 2006
PubMed
Summary

Vascular disrupting agents (VDAs) offer a novel cancer treatment by collapsing tumor blood vessels, unlike antiangiogenesis drugs. This review covers six small molecule VDAs and their clinical progress.

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