Measurement of remote memory pre- and post-temporal lobectomy: a longitudinal case study

There is evidence that remote memory is affected by temporal lobe epilepsy (TLE) and by temporal lobectomy (TL) for the relief of epilepsy. However, remote memory is not routinely assessed when patients with epilepsy undergo neuropsychological testing either pre- or postsurgery. We present a literature review and detailed longitudinal case study of a woman (A.Z.) who had right TLE and fears about deterioration of her remote memory following right TL. Remote memory was assessed by conventional methods (remote memory questionnaire for public events) and by a novel method of seeking vividness ratings for elicited autobiographical memories with A.Z.'s partner acting as the control. A.Z.'s level of memory for remote/recent public events and her rate of forgetting were the same as her partner's, both before and after surgery. A.Z.'s vividness ratings for her own autobiographical memories were similar to her partner's ratings for his memories. Her vividness ratings for her partner's memories that involved events common to both of them were slightly lower than his. A.Z.'s rate of forgetting of her own and her partner's memories was the same as that of her partner, both before and after surgery. There are two principal conclusions. First, this assessment method of measuring remote memory is easy to use and captured the patient's clinical concerns. Second, applying the methodology in this single case suggested that right-sided unilateral TLE and TL may pose no threat to remote memory.