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Related Experiment Videos

Dense gas processing of polymeric controlled release formulations.

Andrian Tandya1, Raffaella Mammucari, Fariba Dehghani

  • 1School of Chemical Engineering and Industrial Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.

International Journal of Pharmaceutics
|October 31, 2006
PubMed
Summary
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Dense gas technology offers efficient pharmaceutical processing for heat-sensitive compounds. These techniques enable controlled release formulations, micronization, and high-purity particle crystallization.

Area of Science:

  • Pharmaceutical Science
  • Chemical Engineering

Background:

  • Dense gases, near their critical points, exhibit unique properties.
  • They offer liquid-like solvation and gas-like mass transfer for processing.
  • Ideal for heat-labile compounds like proteins and pharmaceuticals.

Purpose of the Study:

  • To provide an overview of dense gas techniques.
  • To explore fabrication of polymeric drug formulations for controlled release.

Main Methods:

  • Utilizing dense gas properties for extraction, separation, and synthesis.
  • Applying moderate operating conditions suitable for sensitive materials.

Main Results:

  • Dense gas techniques facilitate micronization and crystallization.

Related Experiment Videos

  • Enables preparation of microencapsulated drug formulations.
  • Suitable for sterilization and high-purity particle production.

    • Conclusions:

    • Dense gas technology is a versatile tool for pharmaceutical processing.
    • Facilitates advanced drug delivery systems and particle engineering.