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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: Jul 19, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

[What should be done when laser iridotomy does not physically eliminate angle closure?].

F Valtot1

  • 1Institut du Glaucome - Fondation Hôpital St Joseph - 185 rue Raymond Losserand - 75014 Paris.

Journal Francais D'Ophtalmologie
|October 31, 2006
PubMed
Summary

Primary angle closure is often caused by pupillary block, managed with laser iridotomy. Other mechanisms may require iridoplasty or lens extraction for effective angle closure treatment.

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Last Updated: Jul 19, 2026

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Area of Science:

  • Ophthalmology
  • Glaucoma Research

Context:

  • Angle closure glaucoma is a significant cause of vision loss.
  • Pupillary block is the most common mechanism in primary angle closure.
  • Existing treatments may not fully resolve all cases of angle closure.

Purpose:

  • To review the mechanisms of angle closure.
  • To discuss the efficacy of various surgical interventions for angle closure glaucoma.
  • To highlight alternative and advanced treatment strategies.

Summary:

  • Pupillary block is the primary driver of angle closure glaucoma, effectively managed with laser iridotomy.
  • When pupillary block is not the sole mechanism or when synechiae are present, iridoplasty and lens extraction (with goniosynechialysis if needed) are effective alternatives.
  • Trabeculectomy offers a later, safer option, though malignant glaucoma is a potential complication in primary angle closure cases.

Impact:

  • Provides a comprehensive overview of angle closure management strategies.
  • Informs clinical decision-making for complex and refractory cases of angle closure glaucoma.
  • Contributes to understanding the nuances of surgical interventions for preserving vision.