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[Spondylarthritides].

J Braun1, J Sieper

  • 1Abteilung für Gastroenterologie und Rheumatologie, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin. J.Braun@rheumazentrum-ruhrgebiet.de

Zeitschrift Fur Rheumatologie
|October 31, 2006
PubMed
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Ankylosing spondylitis (AS) is a type of spondyloarthritis (SpA). Early diagnosis of AS is improving with new methods like HLA B27 testing and MRI, aiding timely treatment.

Area of Science:

  • Rheumatology
  • Immunology
  • Radiology

Background:

  • Ankylosing spondylitis (AS) is a primary subtype of spondyloarthritides (SpA).
  • Key features include inflammatory back pain, peripheral oligoarthritis, and enthesitis.
  • Current classification criteria are less effective in early disease stages, leading to diagnostic delays.

Purpose of the Study:

  • To review advancements in early diagnosis of AS.
  • To highlight current management recommendations for AS and SpA.

Main Methods:

  • Review of diagnostic advancements including HLA B27 and advanced imaging (MRI).
  • Discussion of conventional radiography as the gold standard.
  • Summary of international management guidelines.

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Main Results:

  • Early diagnosis of AS is enhanced by HLA B27 and MRI of sacroiliac joints and spine.
  • Conventional radiography remains the definitive diagnostic tool.
  • Management strategies include NSAIDs, sulfasalazine for peripheral arthritis, anti-TNF agents for active disease, and physiotherapy.

Conclusions:

  • Improved diagnostic methods are crucial for timely intervention in AS.
  • Comprehensive management involving pharmacotherapy and physiotherapy is essential for SpA patients.