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Updated: Jul 19, 2026
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Intensified neoadjuvant radiochemotherapy for locally advanced rectal cancer: a review
Gunther Klautke1, Rainer Fietkau
1Klinik und Poliklinik für Strahlentherapie der Universität Rostock, Rostock, Germany. gunther.klautke@med.uni-rostock.de
Background:
The rate of local recurrence of locally advanced rectal cancer (stage III and IV according to the criteria of Union Internationale Contre Le Cancer) is still high, and also the rate of distant metastases. There are a lot of phase I/II trails of intensified neoadjuvant radiochemotherapy with different chemotherapeutic agents and current protocols to radiotherapy.
Aim:
The objective of this review of literature was to evaluate the necessity, the results, and comparability of the different regimes and to evaluate a potential impact on later adjuvant chemotherapy.
