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Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
Spinal intramedullary metastasis of medulloblastoma at initial diagnosis
Tomoo Inoue1, Toshihiro Kumabe, Toshiyuki Takahashi
1Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.
Case Report:
Spinal magnetic resonance imaging of a 4-year-old boy with medulloblastoma at the initial presentation showed intramedullary lesion without enhancement effect and slight cord swelling from C-5 to T-1. After complete response to the initial therapy, this lesion recurred and slowly expanded. Cervical 11C-methionine-positron emission tomography could establish the diagnosis of intramedullary metastasis.
Conclusion:
Spinal intramedullary metastasis of medulloblastoma at initial diagnosis is extremely rare, but must be considered.

