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Updated: Jul 19, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
Published on: April 25, 2014
Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic
Laurent X Nouvel1, Eric Kassa-Kelembho, Tiago Dos Vultos
1Institut Pasteur, Paris, France.
Abstract:
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
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