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Nicorandil related anal ulcer
Z Al-Hilli1, R Pritchard, G Roche-Nagle
1Dept of Colorectal Surgery, Beaumont Hospital, Dublin 9.
Irish Journal of Medical Science
|November 1, 2006
Summary
Anal ulceration is a rare condition. This case study highlights nicorandil as a potential cause, emphasizing the need for prompt diagnosis and management.
Area of Science:
- Gastroenterology
- Cardiology
Background:
- Anal ulceration is an uncommon condition presenting with severe pain, bleeding, and discharge.
- Differential diagnosis includes anal carcinoma and other rare causes.
Observation:
- A 74-year-old female patient experienced severe anal pain and ulceration.
- The symptoms were linked to nicorandil, a potassium channel activator used for angina treatment.
Findings:
- Discontinuation of nicorandil led to symptom relief.
- Faecal diversion also contributed to ulcer healing.
Implications:
- Recognizing the association between nicorandil and anal ulceration is crucial for accurate diagnosis.
- This knowledge aids in effective management strategies for patients presenting with anal ulceration.
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