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Updated: Jul 19, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
Taxane-resistant lymphoepithelial-like carcinoma: excellent response to VIP chemotherapy
A G Duffy1, G Wyse, A M Horgan
1Dept of Medical Oncology, Mercy University Hospital, Cork. austinduffy@hotmail.com
Background:
Lymphoepithelial-like carcinoma is a rare tumour type. The optimal treatment for this disease is not known. No effective therapies are described in the literature.
Aims:
This report describes a case of lymphoepithelial-like carcinoma and documents a therapeutic strategy which has proved effective.
Results:
The patient was initially treated with a common platinum-based chemotherapy regimen incorporating a taxane (Carbplatin and Docetaxel). Disease stabilization initially occurred but the patient soon progressed. The patient was then treated with VIP chemotherapy and had a complete response.
Conclusion:
VIP chemotherapy appears to be an effective therapeutic strategy in lymphoepithelial-like carcinoma.
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