Related Experiment Video
Updated: Jul 19, 2026

Whole-Kidney Three-Dimensional Staining with CUBIC
Published on: July 18, 2022
Collecting duct carcinoma of the kidney: a case report with variable immunohistochemistry
R M Connolly1, P Downey, J A McCaffrey
1Dept of Medical Oncology , Mater Misericordiae Hospital, Dublin, Ireland. roisinconnolly@gmail.com
Background:
Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course.
Aims:
We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management.
Results:
Our patient died shortly after commencing systemic chemotherapy.
Conclusion:
Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.
