Related Experiment Video
Updated: Feb 8, 2026

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
Published on: August 21, 2019
TreePlus: interactive exploration of networks with enhanced tree layouts
Bongshin Lee1, Cynthia S Parr, Catherine Plaisant
1Human-Computer Interaction Lab, Department of Computer Science, University of Maryland, College Park 20742, USA. bongshin@cs.umd.edu
Visual analytics tools struggle with large, dense graphs. TreePlus, a novel tree-style layout, enhances graph visualization and interaction, improving user understanding and confidence, especially with complex data.
Area of Science:
- Information Visualization
- Human-Computer Interaction
- Visual Analytics
Background:
- Effective interactive layouts for large graphs remain a challenge.
- Dense layouts and occlusion hinder comprehension of complex networks like food webs, ontologies, and social networks.
Purpose of the Study:
- To introduce TreePlus, an interactive visual analytics component designed to improve graph readability and interaction.
- To evaluate the effectiveness of TreePlus compared to traditional graph interfaces for graph exploration tasks.
Main Methods:
- Developed TreePlus, a novel component utilizing a tree-style layout and a 'plant a seed and grow' interaction metaphor.
- Conducted a controlled user study with 28 participants comparing TreePlus against a traditional graph interface.
- Assessed performance across six distinct graph exploration tasks.
Main Results:
- TreePlus demonstrated increasing advantages over traditional interfaces as data density rose.
- Participants reported higher confidence in their answers when using TreePlus.
- A majority of participants expressed a preference for the TreePlus interface.
Conclusions:
- TreePlus effectively reveals graph structure and enhances readability for complex datasets.
- The 'plant a seed and grow' metaphor supports local graph exploration and information gathering.
- TreePlus offers a promising alternative for interactive analysis of large, dense graphs.
Related Concept Videos
Phylogenetic Trees
The Tree of Life - Bacteria, Archaea, Eukaryotes
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Survival Tree
Building a Survival Tree
Constructing a...
Predator-Prey Interactions
The Bronchial Tree
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...

