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Autoimmune Disorders

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...

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Related Experiment Video

Updated: Jul 19, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

Published on: June 26, 2018

New analytical tools for studying autoimmune diseases.

Matthias Kalbas¹, Angelika Lueking, Axel Kowald

¹Protagen AG, Otto-Hahn-Str. 15, D-44227 Dortmund, Germany. matthias.kalbas@protagen.de

Current Pharmaceutical Design

|November 1, 2006

Summary

Protein microarrays offer advanced analytical tools for complex samples, improving throughput and multiplexing capabilities. This technology shows great potential for research and diagnostics, particularly in studying autoimmune diseases.

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Last Updated: Jul 19, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

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Published on: June 26, 2018

Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis

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Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Published on: January 2, 2011

Area of Science:

Biotechnology
Analytical Chemistry
Immunology

Background:

Protein microarrays are emerging analytical tools with immobilized proteins.
They address limitations in sample volume and throughput for complex biological samples.
These arrays offer significant potential for multiplexing and high-throughput analysis.

Purpose of the Study:

To describe new applications of protein microarrays in autoimmune disease research.
To discuss bioinformatic tools for data analysis, including normalization, clustering, and classification.
To present the potential of protein microarray technology and future diagnostic requirements.

Main Methods:

Review of recent advances in protein microarray technology.
Discussion of bioinformatic approaches for protein microarray data analysis.
Exploration of applications in autoimmune disease research and diagnostics.

Main Results:

Protein microarrays provide enhanced capabilities for sample volume and throughput.
New applications in studying autoimmune diseases have been identified.
Bioinformatic tools are crucial for effective data analysis and interpretation.

Conclusions:

Protein microarrays are powerful tools for research and diagnostics.
Further development is needed for widespread protein microarray-based diagnostics.
The technology holds significant promise for advancing the study of complex diseases.