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Updated: Jul 19, 2026

Innovative Strategies for Organ Preservation in Heart Transplantation: Uniform Cooling Preservation and Ex-situ Normothermic Perfusion
Published on: November 28, 2025
Preservation solutions for solid organ transplantation
C H Wilson1, N R Brook, D Talbot
1The Liver/ Renal Unit, The Freeman Hospital, High Heaton, Newcastle-upon-Tyne, NE7 7DN, UK. c4moon@doctors.org.uk
Abstract:
Solid organ transplantation was one of the greatest medical advances of the 20th century. Current preservation technology falls short of maintaining organs ex vivo in perpetuity. This review examines the biochemical basis of organ degradation in response to ischaemia, preservation solution composition and potential future organ preservation technology.
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