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Updated: Jul 19, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

[Noncardiac chest pain and gastroesophageal reflux in children]

Tian-lin Wang1, Ke-rong Peng, Mi-zu Jiang

  • 1The Affiliated Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. mizu@zju.edu.cn

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases
|November 1, 2006
PubMed

Insights

Gastroesophageal reflux (GER) is common in children with noncardiac chest pain (NCCP). Esophageal pH monitoring aids in diagnosing NCCP and predicting treatment outcomes in pediatric patients.

Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Medicine

Context:

  • Noncardiac chest pain (NCCP) is a common presenting complaint in children.
  • The differential diagnosis for NCCP can be broad, including gastroesophageal reflux (GER).
  • Accurate diagnosis is crucial for effective management and to rule out more serious conditions.

Purpose:

  • To investigate the association between NCCP and GER in pediatric patients.
  • To evaluate the diagnostic utility of 24-hour ambulatory esophageal pH monitoring in identifying GER in children with NCCP.
  • To assess the predictive value of esophageal pH monitoring for therapeutic response.

Summary:

  • A study involving 36 children with NCCP found significantly higher rates of acid reflux events and prolonged reflux episodes compared to a control group, as measured by esophageal pH monitoring.
  • Of the 20 patients who underwent endoscopy, 11 had esophagitis, and these patients showed a higher prevalence of GER (81.8%) compared to those without esophagitis (33.3%).
  • Esophageal pH monitoring demonstrated significant differences in reflux parameters between patients with and without esophagitis, indicating its diagnostic value.

Impact:

  • This research highlights GER as a frequent cause of NCCP in children.
  • Esophageal pH monitoring is confirmed as a valuable tool for diagnosing GER in pediatric NCCP cases.
  • The findings suggest that esophageal pH monitoring offers both diagnostic and therapeutic predictive insights for managing NCCP in children.
Abstract

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