Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Frontotemporal dementia.

Erik D Roberson1

  • 1Memory and Aging Center, Department of Neurology, University of California San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. eroberson@gladstone.ucsf.edu

Current Neurology and Neuroscience Reports
|November 1, 2006
PubMed
Summary

Frontotemporal dementia (FTD) presents complex syndromes and pathology. Recent advances in clinicopathologic correlations and genetic studies are improving our understanding and navigation of FTD.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Features predicting data exclusion in imaging studies of Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Variations in the effect of pulse pressure on cognition based on blood pressure.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same author

Factors influencing accelerated progression in behavioral variant frontotemporal dementia.

Journal of neurology·2026
Same author

Parvalbumin Neuron-Targeted Loss of Alzheimer's Disease Risk Gene <i>BIN1</i> Is Insufficient to Drive Cognitive or Network Excitability Changes.

eNeuro·2026
Same author

Cholecalciferol (vitamin D3) is an agonist of the Alzheimer's disease-associated immune receptor TREM2.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same author

Linking Cognitive Variability and Alzheimers Disease Biomarkers by Neurocognitive Status.

medRxiv : the preprint server for health sciences·2026

Area of Science:

  • Neurology
  • Neuroscience
  • Genetics

Background:

  • Frontotemporal dementia (FTD) encompasses diverse clinical syndromes with varied pathological substrates.
  • The complexity of FTD has historically made it challenging to study and treat.
  • Recent breakthroughs are enhancing the navigability of FTD research.

Purpose of the Study:

  • To review the clinical presentations and current treatments for FTD.
  • To explore recent advancements in understanding FTD pathophysiology.
  • To highlight the significance of clinicopathologic correlations and genetic discoveries in FTD.

Main Methods:

  • Literature review of clinical presentations and treatments for FTD.
  • Analysis of recent research on FTD pathophysiology.
  • Survey of studies correlating clinical subtypes with pathological substrates.
  • Examination of genetic studies identifying novel FTD causes.

Main Results:

  • Clinicopathologic correlations aid in predicting the pathological substrate for specific FTD clinical subtypes.
  • Genetic studies have been instrumental in uncovering new etiologies for FTD.
  • Progress in understanding FTD pathophysiology is making the disease more navigable.

Conclusions:

  • Recent discoveries are simplifying the complex landscape of Frontotemporal dementia.
  • Clinicopathologic and genetic insights are crucial for advancing FTD research and treatment.
  • The field of FTD is experiencing renewed interest due to these significant scientific advances.

Related Experiment Videos