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Primary synovial sarcoma.

Morris E Hartstein1, Frankie-Lynn Silver, Olivia J Ludwig

  • 1Department of Ophthalmology, Saint Louis University Eye Institute, Saint Louis University School of Medicine, St. Louis, Missouri 63104, USA. mhartstein@earthlink.net

Ophthalmology
|November 1, 2006
PubMed
Summary
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This case report details a rare orbital synovial sarcoma in a 14-year-old, the youngest documented. Successful surgical treatment resulted in no recurrence during follow-up.

Area of Science:

  • Ophthalmology
  • Oncology
  • Pathology

Background:

  • Synovial sarcoma is a rare soft tissue malignancy.
  • Orbital involvement is exceptionally uncommon, with few cases reported.
  • Early diagnosis and treatment are crucial for managing orbital tumors.

Observation:

  • A 14-year-old male presented with a histologically confirmed orbital synovial sarcoma.
  • Diagnosis was supported by specific chromosomal translocation identified via polymerase chain reaction (PCR).
  • The patient underwent complete tumor excision via orbital exenteration.

Findings:

  • Complete tumor resection was achieved.
  • The patient showed no signs of recurrence after 18 months of follow-up.
  • This represents the fourth reported case of orbital synovial sarcoma and the youngest patient diagnosed at 14 years old.

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Implications:

  • Highlights the importance of considering rare diagnoses in orbital masses.
  • Demonstrates the potential efficacy of surgical management for orbital synovial sarcoma.
  • Contributes to the limited literature on pediatric orbital sarcomas.