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T-cell lymphoma presenting with neurologic features in immunocompetent children
Alexander G Bassuk1, Nimish A Mohile, Cynthia Stack
1Departments of Pediatrics and Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA. abassuk@childrensmemorial.org
Abstract:
Systemic T-cell lymphoma presenting with neurologic symptoms is infrequently reported in immunocompetent children. We investigated the presenting features in all 20 immunocompetent children diagnosed with T-cell lymphoma at our institution from 1992-2004. Four children presented with neurologic features. These findings suggest that early neurologic involvement of T-cell lymphoma in immunocompetent children is underrecognized and that central nervous system involvement in these patients should be more thoroughly investigated.
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