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In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay
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Published on: May 5, 2020

Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a

Melissa M Harrison1, Craig J Ceol, Xiaowei Lu

  • 1Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Proceedings of the National Academy of Sciences of the United States of America
|November 1, 2006
PubMed
Summary

The Caenorhabditis elegans synthetic multivulva (synMuv) genes, including lin-37 and lin-54, form a conserved complex that represses vulval cell fate. This complex is essential for developmental regulation and chromatin remodeling.

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