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Updated: Jul 19, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Does arterial stiffness predict atherosclerotic coronary events?
Carmel M McEniery1, John R Cockcroft
1Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
Arterial stiffness, a simple noninvasive measure, is a key indicator for predicting coronary heart disease events. Early identification and risk stratification are crucial for managing cardiovascular disease in aging populations.
Area of Science:
- Cardiovascular Medicine
- Gerontology
- Vascular Biology
Background:
- Coronary heart disease (CHD) remains a leading cause of mortality and morbidity globally.
- Increased longevity leads to a greater overlap between age-related vascular changes and atherosclerosis driven by risk factors.
- Effective early identification and risk stratification are essential for managing cardiovascular risk.
Purpose of the Study:
- To review the predictive value of arterial stiffness for coronary events.
- To explore the pathophysiological mechanisms linking arterial stiffness and atherosclerosis.
Main Methods:
- Literature review focusing on current evidence.
- Analysis of studies measuring arterial stiffness noninvasively in large populations.
Main Results:
- Arterial stiffness is a significant determinant of cardiovascular risk.
- Noninvasive measurement of arterial stiffness is feasible in large populations.
- Evidence supports the predictive value of arterial stiffness for coronary events.
Conclusions:
- Arterial stiffness is a valuable marker for cardiovascular risk stratification.
- Understanding the link between arterial stiffness and atherosclerosis can improve CHD prevention strategies.
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Atherosclerosis I: Introduction
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Coronary Artery Disease II: Pathophysiology
