Related Experiment Video
Updated: Jul 19, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Prevalence and risk factors for iron deficiency in Kelantanese pre-school children
A S Siti-Noor1, W M Wan-Maziah, M Y Narazah
1Department of Paediatrics, Faculty of Medicine, International Islamic University Malaysia, Jalan Hospital, Kuantan 25150, Pahang, Malaysia. sitinooralishibramulisi@yahoo.co.uk
Insights
Iron deficiency (ID) and iron deficiency anaemia (IDA) are highly prevalent in Kelantanese children. Prolonged breastfeeding and not introducing formula milk are key risk factors for ID in this population.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- High prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) in Kelantanese pre-school children.
- Need to identify predictive risk factors for ID in this population.
Purpose of the Study:
- Determine the prevalence of ID and IDA in Kelantanese pre-school children.
- Identify risk factors that predict the presence of ID.
Main Methods:
- Study included 490 children aged 8-26 months from primary health clinics in Kota Bharu, Kelantan.
- Data collected via parental interviews on risk factors and blood analysis for hemoglobin (HB) and serum ferritin (SF).
- Multiple logistic regression used to compare risk factors between iron-deficient and iron-sufficient groups.
Main Results:
- 65.1% of children had anaemia (HB < 11.0 g/dL).
- 38.9% had ID (SF < 12 µg/L), and 31.6% had IDA.
- Independent risk factors for ID included prolonged breastfeeding (>6 months) and failure to receive formula milk.
Conclusions:
- High prevalence of ID and IDA in Kelantanese children.
- Prolonged breastfeeding and lack of formula milk introduction are primary contributors to ID.
- Findings highlight the need for targeted nutritional interventions.
Introduction:
To determine the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) in Kelantanese pre-school children and to identify risk factors that best predict the presence of ID.
Methods:
Children (aged eight to 26 months) who attended eight primary health clinics in the district of Kota Bharu, Kelantan, Malaysia, from September to November 1999, were invited to participate in the study. Parents were interviewed for potential risk factors of ID and blood was taken for the analysis of haemoglobin (HB), mean corpuscular volume and serum ferritin (SF) level after obtaining a verbal consent. The possible risk factors for ID were compared between the iron deficient (SF less than 12 microgrammes per litre) and iron sufficient (SF greater than 12 microgrammes per litre) groups using multiple logistic regression.
Results:
Among 490 children, 319 (65.1 percent, 95 percent confidence interval [CI] 60.7- 69.2 percent) had anaemia (HB less than 11.0 g/dL). 191 children (38.9 percent, 95 percent CI 34.7-43.5 percent) had ID. 155 children (31.6 percent, 95 percent CI 27.6-36.0 percent) had IDA (HB less than 11.0 g/dL and SF less than 12 microgrammes per litre). Independent risk factors for ID were prolonged breast feeding for more than six months (p-value is 0.003, adjusted odds ratio [OR] 2.5, 95 percent CI 1.5-4.0) and failure to receive formula milk (p-value is 0.004, adjusted OR 1.6, 95 percent CI 1.2-2.0). Other dietary factors were not significantly associated with ID.
Conclusion:
The prevalence of ID and IDA among Kelantanese children is high, and is mainly attributed to prolonged breast feeding beyond six months of age and failure to introduce formula milk at later infancy.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Environmental Influences on Intelligence
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Drug Distribution

