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Updated: Jul 19, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Compliance endogenous and exogenous estriol in clinical practice]
Beata Ciszko1, Zygmunt Zdrojewicz
1Klinika Ginekologii II Katedry Ginekologii i Połoznictwa AM we Wrocławiu.
Abstract:
The aim of this study is presenting contemporary datas of the chemical structure, clinical meanings and the role of the weakest estrogen-estriol. Measurement of the level of estriol can serve as a marker of fetus's well-being, can detect some congenital diseases like: Down syndrome, trisomy 18. Inappropriate values of E3 are often associated with high risk pregnancies like: pregnancy-induced hypertension, miscarriage, preterm delivery or intrahepatic cholestasis. It seems, that estriol can be used in hormonal replacement therapy. Some experiments on animals indicates, that estriol administration can be effective in the treatment some autoimmunological diseases.
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