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Updated: Jul 19, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

[The problem of indexation of left ventricular myocardial mass by body size in obese patients]

M M Saltykova, A N Rogoza, E V Oshchepkova

    Terapevticheskii Arkhiv
    |November 2, 2006
    PubMed

    Insights

    The Cornell product (Crn-P) electrocardiogram (ECG) criterion is most sensitive for detecting left ventricular myocardial hypertrophy (LVH) in hypertensive patients, regardless of body mass. Its effectiveness is influenced by body mass index and gender.

    Area of Science:

    • Cardiology
    • Medical Diagnostics

    Background:

    • Hypertension is a significant risk factor for cardiovascular diseases.
    • Left ventricular myocardial hypertrophy (LVH) is a common complication of hypertension.
    • Accurate detection of LVH is crucial for risk stratification and management.

    Purpose of the Study:

    • To evaluate the diagnostic efficacy of various electrocardiogram (ECG) criteria for left ventricular myocardial hypertrophy (LVH).
    • To assess how body mass, including obesity, influences the sensitivity of these ECG criteria in hypertensive patients.

    Main Methods:

    • Analysis of ECG data from 100 hypertensive patients (grades 1-2).
    • Assessment of LVH using Sokolov-Lion (S-L), Cornell voltage (Crn-V), and Cornell product (Crn-P) criteria.
    • Categorization of patients into normal weight, overweight, and obese groups based on body mass index.

    Main Results:

    • The Cornell product (Crn-P) criterion demonstrated the highest sensitivity across all body mass groups.
    • The sensitivity of ECG criteria for LVH varied based on the specific criterion used, patient gender, and body mass index.
    • Indexation methods and excessive body mass significantly impacted the informative value of ECG criteria.

    Conclusions:

    • The Cornell product (Crn-P) is a highly sensitive ECG criterion for LVH in hypertensive individuals, even with varying body mass.
    • The diagnostic accuracy of ECG criteria for LVH is modulated by the chosen indexation method and the degree of overweight or obesity.
    Abstract

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