Related Experiment Video
Updated: Jul 19, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Artificial sun protection: sunscreens and their carrier systems
J R Villalobos-Hernández1, C C Müller-Goymann
1Institut für Pharmazeutische Technologie, Technische Universität Braunschweig, Braunschweig, Germany.
Abstract:
The formulation of sunscreens products requires information about the properties of the substances responsible for the sun protection, their action mechanisms and the vehicles used for their administration. The improvement of the performance of sunscreen substances by a modification of their chemical, physical and technological properties or by the use of conventional and novel carriers is described in this review. The sun protection achieved by the use of sunscreens incorporated into carriers in terms of the sun protection factor (SPF) and other performance indices is also shown. Current manufacturing methods to incorporate sunscreen substances into vehicles are briefly described. Furthermore, basic information related to the dermatological effects of the UV radiation classified according to the different spectral regions of the UV radiation is presented in this manuscript.
Related Concept Videos
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Modified-Release Drug Delivery Systems: Site-Targeted
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Transdermal Drug Delivery Systems
Carrier-Mediated Transport
Active transport involves two types of membrane-spanning transporters: uptake and efflux. Uptake transporters are expressed in the small...
