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Related Experiment Video

Updated: Jul 19, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

Ameloblastoma: a rare nasal polyp.

D Bray¹, A Michael, D T Falconer

¹Department of Otolaryngology, Harold Wood Hospital, Romford, UK. dbray@doctors.org.uk

The Journal of Laryngology and Otology

|November 2, 2006

Summary

Maxillary ameloblastoma, a rare tumor, can cause nasal symptoms. This case highlights a novel surgical approach combining maxillotomy and endoscopic ethmoidectomy for effective treatment.

Area of Science:

Oral and Maxillofacial Surgery
Otorhinolaryngology
Oncology

Background:

Ameloblastoma is a benign odontogenic neoplasm originating from the enamel organ.
Maxillary ameloblastomas are rare and can present with atypical symptoms, mimicking sinonasal diseases.
Early diagnosis and appropriate management are crucial due to the potential for local destruction.

Observation:

A case of maxillary ameloblastoma presenting with nasal obstruction and rhinorrhea is described.
The patient had no prior dental history, making the diagnosis challenging.
The lesion exhibited significant destructive potential within the maxilla.

Findings:

This is the second reported case of maxillary ameloblastoma with these presenting symptoms in English literature.

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Last Updated: Jul 19, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

The first successful excision using a combined maxillotomy and endoscopic ethmoidectomy approach was performed.

Histopathological examination confirmed the diagnosis of ameloblastoma.

Implications:

Maxillary ameloblastoma should be considered in the differential diagnosis of unexplained nasal and maxillary masses.
Combined surgical techniques may offer an effective treatment option for complex maxillary ameloblastomas.
Further research into the management of rare odontogenic neoplasms is warranted.