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Updated: Jul 19, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
Non-small cell lung carcinoma metastatic to the kidney
Ithaar H Derweesh1, Hazem R Ismail, Cristina Magi-Galluzzi
1Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Introduction:
Renal metastasis by non-small cell lung cancer is uncommon and usually described at autopsy.
Case Presentation:
We report the rare case of a 77-year-old man with localized non-small cell lung carcinoma who underwent extirpative surgery and 2 years later presented with gross hematuria and was noted to have a large infiltrating renal mass on computed tomography.
Conclusions:
In patients with a prior history of resected localized non-small cell lung carcinoma, presence of a renal lesion should prompt the clinician to consider the possibility of metastasis. Further evaluation should consider this scenario.
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