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Related Experiment Videos

OmicBrowse: a browser of multidimensional omics annotations.

Tetsuro Toyoda1, Yoshiki Mochizuki, Keith Player

  • 1Genomic Sciences Center, Yokohama Institute, RIKEN, 1-77-22, Suehiro, Tsurumi, Yokohama, Kanagawa, Japan. toyop@gsc.riken.go.jp

Bioinformatics (Oxford, England)
|November 2, 2006
PubMed
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OmicBrowse is a novel browser for exploring integrated omics data across multiple species and datasets. It facilitates gene discovery by connecting genomic and phenomic information, aiding positional cloning efforts.

Area of Science:

  • Genomics
  • Bioinformatics
  • Comparative Genomics

Background:

  • OmicBrowse is developed by the Genome-Phenome Superbrain Project.
  • It is released as free open-source software under the GNU General Public License.
  • Available at http://omicspace.riken.jp.

Purpose of the Study:

  • To introduce OmicBrowse, a browser for exploring multidimensional omics data.
  • To demonstrate its capability in integrating diverse datasets from multiple species.
  • To highlight its utility in positional cloning and candidate gene selection.

Main Methods:

  • Secure peer-to-peer server communications for data integration.
  • Multidimensional omics space for coordinated data exploration.
  • Filtering of gene annotations and documents using keywords and ontology terms.

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Main Results:

  • OmicBrowse provides an integrated view of distributed omics data, including private and public servers.
  • It effectively displays genetic maps and genomic annotations for positional cloning.
  • Omic-space charts are shown to represent schemes for integrating multi-species datasets.

Conclusions:

  • OmicBrowse facilitates exploration of integrated omics knowledge from genomes to phenomes.
  • The browser aids in identifying candidate genes through annotation and document filtering.
  • Omic-space charts offer a robust method for visualizing integrated multi-species omics data.