Sesquiterpene coumarins from the roots of Ferula sinkiangensis and Ferula teterrima
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Published on: February 2, 2024
Jun-Rong Yang1, Zheng An, Zhi-Hong Li
1Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College), Ministry of Education, Beijing, PR China.
Abstract:
Three new natural sesquiterpene coumarins, isofeterin (1), lehmannolol (3), sinkianone (4), and one known compound, lehmannolone (2), were isolated from the roots of Ferula teterrima and Ferula sinkiangensis. Their chemical structures were established on the basis of spectroscopic analysis, including X-ray crystallography and CD spectrum measurements for determining the absolute configuration of compound 2.