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Updated: Jul 19, 2026
09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
The long-term outcome after acute renal failure
1Department of Intensive Care, Austin Hospital, Melbourne, Australia. sean.bagshaw@austin.org.au
Current Opinion in Critical Care
|November 2, 2006
Summary
Long-term survival after acute renal failure is poor, with survival rates varying by time. Most survivors regain independence from renal replacement therapy, but face reduced quality of life.
Area of Science:
- Critical care medicine
- Nephrology
- Prognosis research
Background:
- Critical care research increasingly focuses on long-term outcomes.
- Acute renal failure (ARF) significantly impacts patient prognosis.
Purpose of the Study:
- To review long-term outcomes and prognosis for survivors of acute renal failure.
- To synthesize current knowledge on survival rates, functional recovery, and quality of life post-ARF.
Main Methods:
- Literature review of studies on long-term outcomes after acute renal failure.
- Analysis of survival data at various time points (90 days, 6 months, 1 year, 5 years).
Main Results:
- Variable survival rates for ARF survivors: 46-74% (90 days) to 65-70% (5 years).
- Factors like older age, comorbidities, illness severity, septic shock, and post-cardiac surgery RRT reduce survival.
- 60-70% of survivors regain independence from renal replacement therapy (RRT) within 90 days.
- Survivors report acceptable quality of life but experience mobility issues and limitations in daily activities.
Conclusions:
- Long-term survival following ARF is generally poor.
- Despite poor survival, most ARF survivors recover sufficient renal function to discontinue RRT.
- Survivors experience a diminished quality of life compared to the general population, necessitating further research into morbidity and cost-effectiveness.
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