Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical proteomics: present and future prospects.

Nicole M Verrills1

  • 1Faculty of Health, University of Newcastle, Callaghan, NSW, Australia. nikki.verrills@newcastle.edu.au

The Clinical Biochemist. Reviews
|November 2, 2006
PubMed
Summary

Proteomics research is advancing disease understanding and treatment. Innovations are enabling clinical proteomic profiling for diagnostics and personalized medicine, particularly in cancer.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Inhibitors of the Activity of the Circulating Renin-Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells.

International journal of molecular sciences·2025
Same author

Discovery and Characterization of VPRBP/DCAF1 Kinase Inhibitor Analogs as Microtubular Destabilizing Agents with Potent Antimyeloma Activity.

Molecular cancer therapeutics·2025
Same author

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal.

Leukemia·2025
Same author

Understanding the regulatory landscape of protein phosphatase 2A (PP2A): Pharmacological modulators and potential therapeutics.

Pharmacology & therapeutics·2025
Same author

Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets.

Expert review of proteomics·2024
Same author

Phosphoproteomic analysis of the adaption of epididymal epithelial cells to corticosterone challenge.

Andrology·2024

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Translational Medicine

Background:

  • Proteomics, the study of protein expression and interactions, has identified disease biomarkers and drug targets.
  • Technological advancements are shifting proteomics from discovery research towards clinical applications.

Purpose of the Study:

  • To review recent advances in proteomics technology.
  • To highlight the potential of clinical proteomics in disease diagnosis and treatment.
  • To discuss challenges and future directions for routine clinical implementation.

Main Methods:

  • Review of current proteomics technologies and their applications.
  • Analysis of the role of protein profiling in disease diagnostics and treatment outcome prediction.
  • Discussion of standardization and data dissemination efforts.

Main Results:

  • Proteomics has identified numerous disease biomarkers and potential drug targets.
  • Protein profiles show promise as diagnostic markers and for predicting treatment outcomes, especially in cancer.
  • Screening specific protein biomarker subsets is currently more feasible than large-scale profiling in clinics.

Conclusions:

  • Clinical proteomics is poised to revolutionize personalized medicine.
  • Standardization of methods and data sharing are crucial for routine clinical adoption.
  • Further research and development are needed to overcome remaining technical hurdles for widespread clinical use.

Related Experiment Videos